KINETICS OF THE ENANTIOMERS OF VIGABATRIN AFTER AN ORAL DOSE OF THE RACEMATE OR THE ACTIVE S-ENANTIOMER

被引：78
作者：
HAEGELE, KD
SCHECHTER, PJ
机构：
来源：
CLINICAL PHARMACOLOGY & THERAPEUTICS | 1986年 / 40卷 / 05期
关键词：
D O I：
10.1038/clpt.1986.227
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
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页码：581 / 586
页数：6
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共 13 条
[1]   STEREOCHEMISTRY, A BASIS FOR SOPHISTICATED NONSENSE IN PHARMACOKINETICS AND CLINICAL-PHARMACOLOGY [J].
ARIENS, EJ .
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1984, 26 (06) :663-668
[2]  
BROWNE TR, 1983, EPILEPSIA, V24, P521
[3]  
DANZIN C, 1984, CHEM BIOL ASPECTS VI, P377
[4]   GAMMA-VINYL-GABA - A SINGLE-BLIND TRIAL IN PATIENTS WITH EPILEPSY [J].
GRAM, L ;
LYON, BB ;
DAM, M .
ACTA NEUROLOGICA SCANDINAVICA, 1983, 68 (01) :34-39
[5]  
GRAM L, 1985, ANN NEUROL, V17, P261
[6]  
GROVE J, 1980, LANCET, V2, P647
[7]   DETERMINATION OF THE R(-)-ENANTIOMERS AND S(+)-ENANTIOMERS OF GAMMA-VINYL-GAMMA-AMINOBUTYRIC ACID IN HUMAN-BODY FLUIDS BY GAS-CHROMATOGRAPHY MASS-SPECTROMETRY [J].
HAEGELE, KD ;
SCHOUN, J ;
ALKEN, RG ;
HUEBERT, ND .
JOURNAL OF CHROMATOGRAPHY, 1983, 274 (MAY) :103-110
[8]   GAMMA-VINYL GABA (4-AMINO-HEX-5-ENOIC ACID), A NEW SELECTIVE IRREVERSIBLE INHIBITOR OF GABA-T - EFFECTS ON BRAIN GABA METABOLISM IN MICE [J].
JUNG, MJ ;
LIPPERT, B ;
METCALF, BW ;
BOHLEN, P ;
SCHECHTER, PJ .
JOURNAL OF NEUROCHEMISTRY, 1977, 29 (05) :797-802
[9]   4-AMINO-HEX-5-ENOIC ACID, A SELECTIVE CATALYTIC INHIBITOR OF 4-AMINOBUTYRIC-ACID AMINOTRANSFERASE IN MAMMALIAN BRAIN [J].
LIPPERT, B ;
METCALF, BW ;
JUNG, MJ ;
CASARA, P .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1977, 74 (03) :441-445
[10]   ANTI-CONVULSANT ACTION IN MICE WITH SOUND-INDUCED SEIZURES OF THE OPTICAL ISOMERS OF GAMMA-VINYL GABA [J].
MELDRUM, BS ;
MURUGAIAH, K .
EUROPEAN JOURNAL OF PHARMACOLOGY, 1983, 89 (1-2) :149-152
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