THYMIC EMIGRATION - CONVEYOR BELTS OR LUCKY DIPS

被引：166
作者：
SCOLLAY, R
GODFREY, DI
机构：
[1] Roland Scollay and Dale Godfrey are at the Centenary Institute of Cancer Medicine and Cell Biology, Sydney
来源：
IMMUNOLOGY TODAY | 1995年 / 16卷 / 06期
关键词：
D O I：
10.1016/0167-5699(95)80179-0
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The thymic medulla has always seemed a rather uncomplicated compartment, simply storing mature thymocytes until they are exported to the peripheral lymphoid organs. However, as discussed here by Roland Scollay and Dale Godfrey, a careful look at recent data suggests that events in the medulla may be more complex and protracted than previously thought.
引用
收藏
页码：268 / 273
页数：6
相关论文
共 21 条
[1]   NK1.1+ CD4+ CD8- THYMOCYTES WITH SPECIFIC LYMPHOKINE SECRETION [J].
ARASE, H ;
ARASE, N ;
NAKAGAWA, K ;
GOOD, RA ;
ONOE, K .
EUROPEAN JOURNAL OF IMMUNOLOGY, 1993, 23 (01) :307-310
[2]   CD4+ AND CD8+ T-CELLS ACQUIRE SPECIFIC LYMPHOKINE SECRETION POTENTIALS DURING THYMIC MATURATION [J].
BENDELAC, A ;
SCHWARTZ, RH .
NATURE, 1991, 353 (6339) :68-71
[3]   A SUBSET OF CD4(+) THYMOCYTES SELECTED BY MHC CLASS-I MOLECULES [J].
BENDELAC, A ;
KILLEEN, N ;
LITTMAN, DR ;
SCHWARTZ, RH .
SCIENCE, 1994, 263 (5154) :1774-1778
[4]   RENEWAL AND FATE IN MAMMALIAN THYMUS - MECHANISMS AND INFERENCES OF THYMOCYTOKINETICS [J].
BRYANT, BJ .
EUROPEAN JOURNAL OF IMMUNOLOGY, 1972, 2 (01) :38-&
[5]   INTRATHYMIC PROLIFERATION OF PERINATAL MOUSE ALPHA-BETA-T-CELL AND GAMMA-DELTA-T-CELL RECEPTOR-EXPRESSING MATURE T-CELLS [J].
CEREDIG, R .
INTERNATIONAL IMMUNOLOGY, 1990, 2 (09) :859-867
[6]   KINETICS OF MATURE T-CELL DEVELOPMENT IN THE THYMUS [J].
EGERTON, M ;
SCOLLAY, R ;
SHORTMAN, K .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (07) :2579-2582
[7]  
FISCHER M, 1991, J IMMUNOL, V146, P3452
[8]   CONTROL POINTS IN EARLY T-CELL DEVELOPMENT [J].
GODFREY, DI ;
ZLOTNIK, A .
IMMUNOLOGY TODAY, 1993, 14 (11) :547-553
[9]   A ROLE FOR A PRE-T-CELL RECEPTOR IN T-CELL DEVELOPMENT [J].
GROETTRUP, M ;
VONBOEHMER, H .
IMMUNOLOGY TODAY, 1993, 14 (12) :610-614
[10]   KINETICS AND EFFICACY OF POSITIVE SELECTION IN THE THYMUS OF NORMAL AND T-CELL RECEPTOR TRANSGENIC MICE [J].
HUESMANN, M ;
SCOTT, B ;
KISIELOW, P ;
VONBOEHMER, H .
CELL, 1991, 66 (03) :533-540
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