CYTOGENETIC AND MOLECULAR STUDIES IN THE PRADER-WILLI AND ANGELMAN SYNDROMES - AN OVERVIEW

被引：41
作者：
KNOLL, JHM
WAGSTAFF, J
LALANDE, M
机构：
[1] HARVARD UNIV,CHILDRENS HOSP,SCH MED,DIV GENET,300 LONGWOOD AVE,BOSTON,MA 02115
[2] HOWARD HUGHES MED INST,BOSTON,MA
[3] HARVARD UNIV,SCH MED,DEPT PEDIAT,BOSTON,MA 02115
来源：
AMERICAN JOURNAL OF MEDICAL GENETICS | 1993年 / 46卷 / 01期
关键词：
CHROMOSOME-15; ANGELMAN SYNDROME; PRADER-WILLI SYNDROME;
D O I：
10.1002/ajmg.1320460103
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The majority of patients with Angelman syndrome and Prader-Willi syndrome have a cytogenetic and molecular deletion of chromosome 15911q13 with the primary difference being in the parental origin of deletion. Our current understanding of the cytogenetics and molecular genetics of these 2 clinically distinct syndromes will be discussed in this review.
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页码：2 / &
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