HIGHLY ENANTIOSELECTIVE SYNTHESIS OF PROPARGYLIC ALCOHOLS BY WAY OF THE ASYMMETRIC ALDOL REACTION

被引：17

作者：

MUKAIYAMA, T

FURUYA, M

OHTSUBO, A

KOBAYASHI, S

机构：

来源：

CHEMISTRY LETTERS | 1991年 / 06期

关键词：

D O I：

10.1246/cl.1991.989

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the presence of a catalytic amount of chiral diamine-coordinated tin(II) triflate, acetylenic aldehydes enantioselectively react with silyl enol ethers of thioesters to afford the corresponding aldol-type adducts, propargylic alcohols, in high yields. The products are easily converted to the corresponding optically active allene derivatives via effective chiral transfer.

引用

页码：989 / 992

页数：4

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