QUALITATIVE AND QUANTITATIVE CHANGES IN UTERINE MESSENGER-RNA POPULATIONS IN RESPONSE TO ESTRADIOL TREATMENT OF RATS

被引：20

作者：

AZIZ, S ^{[1
]}

BALMAIN, A ^{[1
]}

KNOWLER, JT ^{[1
]}

机构：

[1] BEATSON INST CANC RES,GLASGOW G61 1BD,SCOTLAND

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1979年 / 100卷 / 01期

关键词：

D O I：

10.1111/j.1432-1033.1979.tb02037.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The mRNA population of immature rat uteri, responding to different lengths of oestradiol‐induced differentiation, have been compared by the technique of DNA hybridization with heterogeneous RNA. Over the first 4 h of hormone induction there are continuing qualitative and quantitative changes in the poly(A)‐containing mRNA such that, by 4 h after oestradiol administration, the population bears little resemblance to that of the unstimulated animal. Between 2 h and 4 h after oestradiol administration, the most striking changes appear to be in sequences of intermediate abundance. The possible significance of these findings is discussed. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：95 / 100

页数：6

共 21 条

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