ANTIBODIES TO PURIFIED INSULIN RECEPTOR HAVE INSULIN-LIKE ACTIVITY

被引：215

作者：

JACOBS, S

CHANG, KJ

CUATRECASAS, P

机构：

来源：

SCIENCE | 1978年 / 200卷 / 4347期

关键词：

D O I：

10.1126/science.663609

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：1283 / 1284

页数：2

共 12 条

[1]

Chernick S, 1969, METH ENZYMOLOGY, V14, P627

[2]

Cuatrecasas P, 1976, Adv Protein Chem, V30, P251, DOI 10.1016/S0065-3233(08)60481-7

[3] AFFINITY CHROMATOGRAPHY AND PURIFICATION OF INSULIN RECEPTOR OF LIVER-CELL MEMBRANES [J].

CUATRECASAS, P .

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[4] ISOLATION OF INSULIN RECEPTOR OF LIVER AND FAT-CELL MEMBRANES [J].

CUATRECASAS, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1972, 69 (02) :318-+

[5] BINDING OF INSULIN AND OTHER HORMONES TO NON-RECEPTOR MATERIALS - SATURABILITY, SPECIFICITY AND APPARENT NEGATIVE-COOPERATIVITY [J].

CUATRECASAS, P ;

HOLLENBERG, MD .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1975, 62 (01) :31-41

[6] INSULIN-LIKE ACTIVITY OF CONCANAVALIN A AND WHEAT-GERM AGGLUTININ - DIRECT INTERACTIONS WITH INSULIN RECEPTORS [J].

CUATRECASAS, P ;

TELL, GPE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (02) :485-489

[7] CHARACTERIZATION OF ANTIBODIES TO INSULIN RECEPTOR - CAUSE OF INSULIN-RESISTANT DIABETES IN MAN [J].

FLIER, JS ;

KAHN, CR ;

JARRETT, DB ;

ROTH, J .

JOURNAL OF CLINICAL INVESTIGATION, 1976, 58 (06) :1442-1449

[8] ANTIBODIES THAT IMPAIR INSULIN RECEPTOR-BINDING IN AN UNUSUAL DIABETIC SYNDROME WITH SEVERE INSULIN RESISTANCE [J].

FLIER, JS ;

KAHN, CR ;

ROTH, J ;

BAR, RS .

SCIENCE, 1975, 190 (4209) :63-65

[9] MODULATION OF ACETYLCHOLINE-RECEPTOR BY ANTIBODY AGAINST RECEPTOR [J].

HEINEMANN, S ;

BEVAN, S ;

KULLBERG, R ;

LINDSTROM, J ;

RICE, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (07) :3090-3094

[10] PURIFICATION AND PROPERTIES OF INSULIN RECEPTORS FROM RAT-LIVER MEMBRANES [J].

JACOBS, S ;

SHECHTER, Y ;

BISSELL, K ;

CUATRECASAS, P .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1977, 77 (03) :981-988

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