CHRONIC INTESTINAL PSEUDOOBSTRUCTION WITH MYOPATHY AND OPHTHALMOPLEGIA - A MUSCULAR BIOCHEMICAL-STUDY OF A MITOCHONDRIAL DISORDER

被引：37

作者：

LI, V

HOSTEIN, J

ROMERO, NB

MARSAC, C

MEZIN, P

BOST, R

DEGOUL, F

FARDEAU, M

FOURNET, J

机构：

[1] HOP A MICHALLON,SERV GASTROENTEROL & HEPATOL,BP 217X,F-38043 GRENOBLE,FRANCE

[2] HOP A MICHALLON,SERV PATHOL CELLULAIRE,GRENOBLE,FRANCE

[3] INSERM,UNITE DEV PATHOL REGENERAT SYST NEUROMUSCULAIRE 153,F-75005 PARIS,FRANCE

[4] INSERM,U75,BIOCHIM LAB,F-75005 PARIS,FRANCE

来源：

DIGESTIVE DISEASES AND SCIENCES | 1992年 / 37卷 / 03期

关键词：

CHRONIC INTESTINAL PSEUDOOBSTRUCTION; OPHTHALMOPLEGIA; MITOCHONDRIAL MYOPATHY; FUNCTIONAL MITOCHONDRIAL DISORDERS;

D O I：

10.1007/BF01307743

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The association of chronic intestinal pseudoobstruction with ophthalmoplegia has been reported previously in visceral myopathies. We report a case of this association in which muscle mitochondria had a crystalline appearance, a dense core, and decreased cytochrome c oxidase and succinate cytochrome c reductase activities. The absence of evident mitochondrial DNA deletion in the skeletal muscle of this patient does not exclude the possibility of localized deletion or mutation of mitochondrial DNA in digestive muscle. © 1992 Plenum Publishing Corporation.

引用

页码：456 / 463

页数：8

共 28 条

[1]

ANURAS S, 1988, ANNU REV MED, V39, P1, DOI 10.1146/annurev.me.39.020188.000245

[2]

ANURAS S, 1983, GASTROENTEROLOGY, V84, P346

[3] MYOINTESTINAL, NEUROINTESTINAL, GASTROINTESTINAL ENCEPHALOPATHY (MNGIE SYNDROME) DUE TO PARTIAL DEFICIENCY OF CYTOCHROME-C-OXIDASE - A NEW MITOCHONDRIAL MULTISYSTEM DISORDER [J].