Cytokines and Intrathecal Synthesis of Oligoclonal IgG in Viliuisk Encephalomyelitis and Multiple Sclerosis Patients

被引：0
|
作者：
Sivtseva, T. M. [1 ,2 ]
Chemezova, R., I [3 ]
Vladimirtsev, V. A. [4 ]
Nikitina, R. S. [5 ]
Danilova, A. P. [6 ]
Popova, T. E. [7 ,8 ]
Okoneshnikova, L. T.
Osakovsky, V. L. [2 ,8 ,9 ]
机构：
[1] Fed State Scientifically Inst, Inst Hlth, Novosibirsk, Russia
[2] North Eastern Fed Univ, Lab Genet Res, Yakutsk, Russia
[3] North Eastern Fed Univ, Clin Diagnost Lab, Yakutsk, Russia
[4] North Eastern Fed Univ, Dept Viliuisk Encephalomyelitis Invest, Yakutsk, Russia
[5] North Eastern Fed Univ, Hosp Inst Hlth, Yakutsk, Russia
[6] North Eastern Fed Univ, Hosp Inst Hlth, Yakutsk, Russia
[7] North Eastern Fed Univ, Med Inst, Yakutsk, Russia
[8] Ctr Multiple Sclerosis Republ Sakha, Yakutia, Russia
[9] Republ Hosp 2, Neurol Dept, Kazan, Russia
来源：
YAKUT MEDICAL JOURNAL | 2011年 / 04期
关键词：
Viliuisk encephalomyelitis; multiple sclerosis; cytokines; intrathecal synthesis of oligoclonal IgG;
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Interleukin 6(IL6), interferon gamma (INF gamma) and interleukin 18 (IL18) were investigated in cerebrospinal fluid (CSF) and serum of Viliuisk encephalomyelitis (VE), multiple sclerosis (MS) and other neurological diseases patients. IL 18 and INF gamma production in VE and MS were significant different. There had been a significant increase of IL 18 in CSF of VE patients and INF gamma in CSF and serum of MS patients. High level of INF gamma in CSF of MS patients was associated with presence of oligoclonal IgG.
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收藏
页码：38 / 44
页数：7
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