PRETREATMENT AND HEAVY-METAL LD50 VALUES

被引:27
作者
JONES, MM [1 ]
SCHOENHEIT, JE [1 ]
WEAVER, AD [1 ]
机构
[1] VANDERBILT UNIV,CTR TOXICOL,NASHVILLE,TN 37235
关键词
D O I
10.1016/0041-008X(79)90274-6
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
LD50 values, with and without pretreatment with the same ion, have been determined in mice for intraperitoneal injection of salts of the ions Cd2+, Hg2+, Ag+, Tl+, Pd2+, Au+, Pt2+, Cu2+, Sn2+, Pt4+, and Zn2+. In the case of Cd2+ the previously reported increase in LD50 values subsequent to pretreatment was confirmed. A statistically significant increase in LD50 values for Hg2+ Ag+, Au+, Cu2+, and Sn2+ subsequent to pretreatment was also observed. © 1979.
引用
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页码:41 / 44
页数:4
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