EVIDENCE FOR A ROLE OF ENDORPHINS IN STRESS-INDUCED AND SUCKLING-INDUCED PROLACTIN-RELEASE IN THE RAT

被引：77
作者：
FERLAND, L
KLEDZIK, GS
CUSAN, L
LABRIE, F
机构：
[1] Medical Research Council Group in Molecular Endocrinology, Le Centre Hospitalier, l'Université Lavai
来源：
MOLECULAR AND CELLULAR ENDOCRINOLOGY | 1978年 / 12卷 / 03期
基金：
英国医学研究理事会;
关键词：
endorphins; opiates; prolactin release;
D O I：
10.1016/0303-7207(78)90085-0
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Injection of the opiate antagonist naloxone completely prevented the rise of serum prolactin induced by ether stress in intact male rats. Naloxone also led to a 50-95% inhibition of the marked elevation of plasma prolactin levels induced by suckling. These data suggest that endogenous opiates (endorphins) are involved in the stimulation of prolactin release induced by both stress and suckling in the rat. © 1978.
引用
收藏
页码：267 / 272
页数：6
相关论文
共 32 条
[1]   NICOTINE BLOCKS SUCKLING-INDUCED RISE IN CIRCULATING PROLACTIN IN LACTATING RATS [J].
BLAKE, CA ;
SAWYER, CH .
SCIENCE, 1972, 177 (4049) :619-&
[2]   STIMULATION OF PITUITARY PROLACTIN AND TSH RELEASE IN LACTATING AND PROESTROUS RATS [J].
BLAKE, CA .
ENDOCRINOLOGY, 1974, 94 (02) :503-508
[3]   POTENT PROLACTIN AND GROWTH-HORMONE RELEASING ACTIVITY OF MORE ANALOGS OF MET-ENKEPHALIN [J].
CUSAN, L ;
DUPONT, A ;
KLEDZIK, GS ;
LABRIE, F ;
COY, DH ;
SCHALLY, AV .
NATURE, 1977, 268 (5620) :544-547
[4]   CHANGES OF PITUITARY THYROTROPIN RELEASING HORMONE (TRH) RECEPTOR LEVEL AND PROLACTIN RESPONSE TO TRH DURING RAT ESTROUS-CYCLE [J].
DELEAN, A ;
GARON, M ;
KELLY, PA ;
LABRIE, F .
ENDOCRINOLOGY, 1977, 100 (06) :1505-1510
[5]   MODULATION OF PITUITARY THYROTROPIN RELEASING HORMONE RECEPTOR LEVELS BY ESTROGENS AND THYROID-HORMONES [J].
DELEAN, A ;
FERLAND, L ;
DROUIN, J ;
KELLY, PA ;
LABRIE, F .
ENDOCRINOLOGY, 1977, 100 (06) :1496-1504
[6]   CHARACTERISTICS OF INTERACTION BETWEEN THYROTROPIN-RELEASING-HORMONE AND SOMATOSTATIN FOR THYROTROPIN AND PROLACTIN-RELEASE [J].
DROUIN, J ;
DELEAN, A ;
RAINVILLE, D ;
LACHANCE, R ;
LABRIE, F .
ENDOCRINOLOGY, 1976, 98 (02) :514-521
[7]   STIMULATION OF PROLACTIN-RELEASE IN RAT BY INTRAVENTRICULAR-INJECTION OF BETA-ENDORPHIN AND METHIONINE-ENKEPHALIN [J].
DUPONT, A ;
CUSAN, L ;
LABRIE, F ;
COY, DH ;
LI, CH .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1977, 75 (01) :76-82
[8]   BETA-ENDORPHIN - STIMULATION OF GROWTH-HORMONE RELEASE INVIVO [J].
DUPONT, A ;
CUSAN, L ;
GARON, M ;
LABRIE, F ;
LI, CH .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (01) :358-359
[9]   EFFECTS OF ACUTE STRESS ON SERUM LH AND PROLACTIN IN INTACT, CASTRATE AND DEXAMETHASONE-TREATED MALE RATS [J].
EUKER, JS ;
MEITES, J ;
RIEGLE, GD .
ENDOCRINOLOGY, 1975, 96 (01) :85-92
[10]   CHANGES OF PITUITARY SENSITIVITY TO LH-RH DURING RAT ESTROUS-CYCLE [J].
FERLAND, L ;
BORGEAT, P ;
LABRIE, F ;
BERNARD, J ;
DELEAN, A .
MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1975, 2 (02) :107-115
1234