MASS-SPECTROMETRY AND LIQUID-CHROMATOGRAPHY - MASS-SPECTROMETRY OF ALPHA-AMINO BETA-NITROSTILBENES

被引：0

作者：

HAYESMAJSTOROVIC, J ^{[1
]}

GUERNETNIVAUD, E ^{[1
]}

GUERNET, M ^{[1
]}

VIEL, C ^{[1
]}

机构：

[1] FAC PHARM TOURS,PHARMACOCHIM PROD NAT & ANAL STRUCT,F-37042 TOURS,FRANCE

来源：

ANALYTICAL LETTERS | 1993年 / 26卷 / 10期

关键词：

(Z)-ALPHA-AMINO BETA-NITROSTILBENES; NITROENAMINES; HPLC; MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY MASS SPECTROMETRY;

D O I：

10.1080/00032719308017465

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

(Z)-alpha-amino beta-nitrostilbenes are obtained by the reaction of either ammonia or primary or secondary amines on (Z)-alpha, beta-dinitrostilbene (DNS). The fragmentometric study of these compounds by electron impact and chemical ionization was carried out. The conditions in which it may be possible to determine the purity of these compounds were obtained by HPLC on reversed phase. However the resolution factor between DNS and benzyl- or phenyl-aminonitroenamine is not sufficient for UV detection; only liquid chromatography-mass spectra coupling with negative ionization enables the detection of the possible presence of DNS in these nitro enamino derivatives.

引用

页码：2239 / 2249

页数：11