A FACILE SYNTHESIS OF ORGANOFLUORINE COMPOUNDS USING A SEMI-MOLTEN MIXTURE OF TETRABUTYLAMMONIUM BROMIDE AND AN ALKALI-METAL FLUORIDE

被引：24

作者：

BHADURY, PS ^{[1
]}

PANDEY, M ^{[1
]}

JAISWAL, DK ^{[1
]}

机构：

[1] DEF RES & DEV ESTAB,DIV SYNTHET CHEM,GWALIOR 474002,INDIA

来源：

JOURNAL OF FLUORINE CHEMISTRY | 1995年 / 73卷 / 02期

关键词：

SEMI-MOLTEN MIXTURE; TETRABUTYLAMMONIUM BROMIDE; ALKALI METAL FLUORIDES; ORGANOFLUORINE COMPOUNDS; NMR SPECTROSCOPY;

D O I：

10.1016/0022-1139(95)03226-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A semi-molten mixture of tetrabutylammonium bromide and an alkali metal fluoride (KF or CsF) has been found to be an efficient reagent system for the preparation of organofluorine compounds, e.g., CH3(CH2)(7)F, CH2=CH-CH2F, FCH2CO2C2H5, C6H5COF, and related compounds through facile fluoride-ion exchange with organohalides. The system provides a simple and convenient alternative to 'anhydrous' tetrabutylammonium fluoride for the synthesis of oragnofluorine compounds.

引用

页码：185 / 187

页数：3

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