VERSATILE SYNTHESIS OF ALICYCLIC AND ACYCLIC COMPOUNDS WITH ALTERNATE AND REMOTE C-METHYL SUBSTITUTION PATTERNS VIA ASYMMETRIC SEQUENTIAL OLEFINATION AND ENE REACTIONS

被引：36

作者：

HANESSIAN, S

BEAUDOIN, S

机构：

[1] Department of Chemistry, Station A, Montréal, Que. H3C 3J7

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 50期

关键词：

D O I：

10.1016/0040-4039(93)88009-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of enantiomerically pure alkyl cyclohexane ethylidene derivatives with 2,3-di-O-benzyl D- and L-glyceraldehyde and related aldehydes in the presence of Lewis acids leads to enantiomerically pure or enriched branched alkylcyclohexenes. These can be oxidized to acyclic motifs with a predetermined C-methyl substitution pattern.

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页码：7659 / 7662

页数：4

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TETRAHEDRON LETTERS, 1992, 33 (50) :7659-7662