Clinical Outcome in Patients with Early versus Delayed Decompression in Cervical Spine Trauma

被引:35
作者
Umerani, Muhammad Sohail [1 ]
Abbas, Asad [1 ,2 ]
Sharif, Salman [1 ]
机构
[1] Liaquat Natl Hosp & Med Coll, Dept Neurosurg, Karachi, Pakistan
[2] Ziauddin Univ Hosp, Dept Surg, J-8 3rd floor,Yaqoob Terrace,Main Gurumandir Rou, Karachi 74800, Pakistan
关键词
Spinal cord injuries; Spinal fractures; Surgical decompression; Spinal fixation; Treatment outcome;
D O I
10.4184/asj.2014.8.4.427
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Study Design: Prospective observational study. Purpose: To assess the clinical outcome after early versus late decompression for traumatic cervical cord injury. Overview of Literature: Traumatic spinal cord injury is common globally with the most tragic outcomes in the cervical spine. Although recent studies have shown that early decompression results in more favourable outcome, its authority is yet to be established. Methods: Study on 98 patients with a traumatic cervical cord injury was conducted over a period of 5 years. The patients who were operated on within 24 hours of the onset of the primary injury (n=34) were classified as the early group, and those who were operated on after 24 hours of the onset of the injury (n=64) were categorized as the late group. The outcome of both the groups was assessed using the American Spinal Injury Association (ASIA) Impairment Scale (AIS) at the 6-month follow-up. Results: The patients in the early group were operated on at a mean time of 18.4 hours (range, 13-24 hours) while patients were operated on at a mean time of 52.7 hours (range, 31-124 hours) in the late group. At the 6-month follow-up, 7 (23.3%) in the early group and 5 (8.7%) in the late group showed >2 grade improvement in the AIS. Conclusions: The results of patients undergoing decompression within 24 hours of the injury are better than those who are operated on later. An attempt should be made to decompress the traumatic cervical spine early in all possible cases.
引用
收藏
页码:427 / 434
页数:8
相关论文
共 27 条
[11]  
Fehlings MG, 2005, CONT MANAGEMENT SPIN, P33
[12]   Early versus Delayed Decompression for Traumatic Cervical Spinal Cord Injury: Results of the Surgical Timing in Acute Spinal Cord Injury Study (STASCIS) [J].
Fehlings, Michael G. ;
Vaccaro, Alexander ;
Wilson, Jefferson R. ;
Singh, Anoushka ;
Cadotte, David W. ;
Harrop, James S. ;
Aarabi, Bizhan ;
Shaffrey, Christopher ;
Dvorak, Marcel ;
Fisher, Charles ;
Arnold, Paul ;
Massicotte, Eric M. ;
Lewis, Stephen ;
Rampersaud, Raja .
PLOS ONE, 2012, 7 (02)
[13]   The Sygen® Multicenter acute spinal cord injury study [J].
Geisler, FH ;
Coleman, WP ;
Grieco, G ;
Poonian, D .
SPINE, 2001, 26 (24) :S87-S98
[14]   Neurologic outcome in conservatively treated patients with incomplete closed traumatic cervical spinal cord injuries [J].
Katoh, S ;
ElMasry, WS ;
Jaffray, D ;
McCall, LW ;
Eisenstein, SM ;
Pringle, RG ;
Pullicino, V ;
Ikata, T .
SPINE, 1996, 21 (20) :2345-2351
[15]  
KORRES DS, 1993, INJURIES CERVICAL SP
[16]   A Systematic Review of Directly Applied Biologic Therapies for Acute Spinal Cord Injury [J].
Kwon, Brian K. ;
Okon, Elena B. ;
Plunet, Ward ;
Baptiste, Darryl ;
Fouad, Karim ;
Hillyer, Jessica ;
Weaver, Lynne C. ;
Fehlings, Michael G. ;
Tetzlaff, Wolfram .
JOURNAL OF NEUROTRAUMA, 2011, 28 (08) :1589-1610
[17]   Does early decompression improve neurological outcome of spinal cord injured patients? Appraisal of the literature using a meta-analytical approach [J].
La Rosa, G ;
Conti, A ;
Cardali, S ;
Cacciola, F ;
Tomasello, F .
SPINAL CORD, 2004, 42 (09) :503-512
[18]   ANTERIOR DECOMPRESSION IN CERVICAL-SPINE TRAUMA - DOES THE TIMING OF SURGERY AFFECT THE OUTCOME [J].
LEVI, L ;
WOLF, A ;
RIGAMONTI, D ;
RAGHEB, J ;
MIRVIS, S ;
ROBINSON, WL .
NEUROSURGERY, 1991, 29 (02) :216-222
[19]  
Lukas R, 2012, ACTA CHIR ORTHOP TR, V79, P233
[20]   Steroids and spinal cord injury: Revisiting the NASCIS 2 and NASCIS 3 trials [J].
Nesathurai, S .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1998, 45 (06) :1088-1093