RELATIONSHIP BETWEEN RNA-CONTENT, CELL-VOLUME AND GROWTH-POTENTIAL IN AGING HUMAN-EMBRYONIC MESENCHYMAL CELLS

被引：8

作者：

WHATLEY, SA

HILL, BT

机构：

[1] IMPERIAL CANC RES FUND LABS,CELLULAR PATHOL LAB,LONDON WC2A 3PX,ENGLAND

[2] IMPERIAL CANC RES FUND LABS,CELLULAR CHEMOTHERAPY LAB,LONDON WC2A 3PX,ENGLAND

来源：

CELL BIOLOGY INTERNATIONAL REPORTS | 1979年 / 3卷 / 08期

关键词：

D O I：

10.1016/0309-1651(79)90098-5

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Modal cell volume and cellular RNA content were measured throughout the lifespan of the human diploid cell line He125. Modal cell volume was found to correlate with both culture replication rate and cellular RNA content. This observation suggests that cell volume changes may be related to the rate of cell division during ageing in vitro, and that both cell volume and RNA content may be closely controlled. There was no change in the relative proportions of the major rRNA species during the cultures' lifespan. © 1979.

引用

页码：671 / 683

页数：13

共 29 条

[1] CLONAL VARIATION AND AGING OF DIPLOID FIBROBLASTS - CINEMATOGRAPHIC STUDIES OF CELL PEDIGREES [J].