CHLAMYDIA-TRACHOMATIS RNA-POLYMERASE ALPHA-SUBUNIT - SEQUENCE AND STRUCTURAL-ANALYSIS

被引:16
作者
GU, LJ
WENMAN, WM
REMACHA, M
MEUSER, R
COFFIN, J
KAUL, R
机构
[1] UNIV CALIF DAVIS,DEPT PEDIAT,DAVIS,CA 95616
[2] UNIV ALBERTA,DEPT PEDIAT,DIV INFECT DIS,EDMONTON,AB T6G 2R7,CANADA
关键词
D O I
10.1128/jb.177.9.2594-2601.1995
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We describe the cloning and sequence analysis of the region surrounding the gene for the alpha subunit of RNA polymerase from Chlamydia trachomatis. This region contains genes for proteins in the order SecY, S13, S11, alpha, and L17, which are equivalent to Escherichia coli and Bacillus subtilis r proteins. The incorporation of chlamydial alpha subunit protein into the E. coli RNA polymerase holoenzyme rather than its truncated variant lacking the amino terminus suggests the existence of structural conservation among alpha subunits from distantly related genera.
引用
收藏
页码:2594 / 2601
页数:8
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