THE EFFECT OF PHYSICOCHEMICAL CHARACTERISTICS OF SYNTHETIC CATIONIC AMPHIPHILES ON DNA TRANSFECTION

被引：6

作者：

AKAO, T

OSAKI, T

MITOMA, JY

ITO, A

KUNITAKE, T

机构：

[1] KYUSHU UNIV, FAC SCI, DEPT CHEM, FUKUOKA 812, JAPAN

[2] KYUSHU UNIV, FAC ENGN, DEPT ORGAN SYNTH, FUKUOKA 812, JAPAN

来源：

CHEMISTRY LETTERS | 1991年 / 02期

关键词：

D O I：

10.1246/cl.1991.311

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Bilayer membranes of double-chain ammoium amphiphiles were utilized for DNA transfection into eukaryotic cells. The efficiency of the DNA transfection was much higher when fluid, vesicler bilayers were used than when rigid, helical bilayers were used.

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页码：311 / 314

页数：4

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