EBV-RELATED CYTOTOXICITY OF FC RECEPTOR NEGATIVE T-LYMPHOCYTES SEPARATED FROM BLOOD OF INFECTIOUS-MONONUCLEOSIS PATIENTS

被引:36
作者
BAKACS, T [1 ]
SVEDMYR, E [1 ]
KLEIN, E [1 ]
ROMBO, L [1 ]
WEILAND, D [1 ]
机构
[1] ROSLAGSTULLS SJUKHUS, S-11422 STOCKHOLM, SWEDEN
基金
美国国家卫生研究院;
关键词
D O I
10.1016/S0304-3835(78)94347-1
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Epstein-Barr virus (EBV) related specific killing was demonstrated previously in the T cell enriched subpopulations of blood lymphocytes of IM patients. In the present work we demonstrate that the cytotoxic cells belong to the Fc negative T subset. T cells in the blood of IM patients can be divided in 2 categories, 1 Fc positive with non discriminative cytotoxicity and the other, Fc negative with selective cytotoxicity against EBV genome carrying lymphoblastoid cell lines. © 1978 Elsevier/North-Holland Scientific Publishers Ltd.
引用
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页码:185 / 189
页数:5
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