RESTRICTION-FRAGMENT-LENGTH-POLYMORPHISM OF THE MAJOR HISTOCOMPATIBILITY COMPLEX-LINKED HEAT-SHOCK PROTEIN-70 (HSP70) GENES OF THE RAT

被引：0
|
作者：
ROTHERMEL, E
WALTER, L
HEDRICH, HJ
GUNTHER, E
机构：
[1] UNIV GOTTINGEN,DIV IMMUNOGENET,D-37073 GOTTINGEN,GERMANY
[2] HANNOVER MED SCH,INST LAB ANIM SCI,HANNOVER,GERMANY
[3] HANNOVER MED SCH,CENT ANIM FACIL,HANNOVER,GERMANY
来源：
JOURNAL OF EXPERIMENTAL ANIMAL SCIENCE | 1994年 / 36卷 / 06期
关键词：
HSP70; GENES; MHC; RFLP; RAT;
D O I：
暂无
中图分类号：
Q95 [动物学];
学科分类号：
071002 ;
摘要：
DNAs from inbred rat strains representing eighteen major histocompatibility complex (RT1) haplotypes have been tested for restriction fragment length polymorphisms of the three heat shock protein 70 (Hsp70) genes mapping into this complex. The DNAs were digested with restriction enzymes BamHI, EcoRI, PstI or PvuII and assayed by probes hybridizing to all three genes or selectively to Hsp70-1, Hsp70-2 and Hsp70-3, respectively. Three to four alleles were detected with each enzyme and in total five different strain distribution patterns could be found. Neither deletions nor amplifications of genes were detected in the three-gene Hsp70 cluster.
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页码：169 / 178
页数：10
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