Variations on a theme: the family of FAD-dependent NAD(P)H-(disulphide)-oxidoreductases

被引：41
作者：
Pai, Emil F. [1 ]
机构：
[1] Max Planck Inst Med Forsch, Heidelberg, Germany
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 1991年 / 1卷 / 05期
关键词：
D O I：
10.1016/0959-440X(91)90181-R
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The term protein 'family' has been used to describe groups of related enzymes that share structural and mechanistic properties. A beautiful example for such an ensemble is the FAD-dependent NAD(P)H-(disulphide)-oxidoreductases. Crystal structures for several family members have recently been determined. They provide interesting clues as to how in evolution a proven form can be changed to satisfy new requirements.
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收藏
页码：796 / 803
页数：8
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