RANDOM GENERATION DEFICIT IN ALCOHOLIC KORSAKOFF PATIENTS

被引:32
|
作者
POLLUX, PMJ
WESTER, A
DEHAAN, EHF
机构
[1] UNIV UTRECHT, DEPT PSYCHON, PSYCHOL LAB, 3584 CS UTRECHT, NETHERLANDS
[2] VINCENT VAN GOGH INST, KORSAKOFF CLIN, 5803 AC VENRAY, NETHERLANDS
关键词
D O I
10.1016/0028-3932(94)00095-7
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Korsakoff's syndrome often affects ''executive'' functions [Baddeley, A. Human Memory, Theory acid Practice, 1990], which in anatomical terms are associated with the frontal lobes. However, in a previous study, Wiegersma, S. and de Jong, E. [J. clin. exp. Neuropsychol. 13, 847-853, 1991] failed to observe a diminished performance on the random generation task, although this task is thought to be sensitive to ''executive'' deficits. In the present study, we sought to replicate and clarify these earlier findings of Wiegersma and de Jong with a group of Korsakoff patients in whom frontal lobe dysfunction was indicated by a reduced performance on fluency tasks. Patients and controls were presented with three tasks. Digit span was used as an index of short term memory capacity; memory search and comparison processes were measured with the missing item scan; and the randomisation task was used to assess the ability to produce non-routine, random sequences. The results showed that the performance of Korsakoff patients declined on the randomisation task while short-term retention and scanning were intact. Analysis of the responses indicated that the Korsakoff patients are able to suppress the dominant response, but have problems in generating and carrying out alternative strategies in novel problem situations.
引用
收藏
页码:125 / 129
页数:5
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