Assisted Reproductive Technologies (ART) in Latin America: The Latin American Registry, 2012

Objective: This report examines information on Assisted Reproduction Technologies performed in Latin America (LA) during 2012. Methods: Multinational data were collected directly from 155 institutions in 14 countries. Individualized, case-bycase data include 47,326 ART cycles covering more than 80% of cycles performed in LA. Treatments included in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), frozen embryo transfers (FET), oocyte donations (OD) and fertility preservation. Results: In 39% of ET IVF/ICSI was performed in women age 35-39 and 31% in women >= 40 years. Delivery rate (DR) per pick-up (OPU) in ICSI and IVF cycles, were 20.9% and 26.5%, respectively. Overall multiple births comprised 20.6% twins and 1.2% triplets. Furthermore, in OD, twins and triplets reached 27.8% and 2.4%, respectively. Pre term births in singletons were 14%. The relative risk of prematurity increased by 4.30 (95% CI 4.1-4.6) in twins, and 43.8 (95% CI 28.5-67.4) in >= triplets. Perinatal mortality increased from 25.2% in singletons, to 44.0% in twins and 80% in >= triplets. Elective single embryo transfer (eSET) was performed in only 1.4% of cycles with DR of 30% in women <= 34 years. Conclusion: Trends over the last 20 years show that eSET should be the way to go provided access is facilitated with public funding.