ASYMMETRIC HYDROLYSIS OF CIS,CIS-5-BENZYLOXY-1,3-DIACETOXYCYCLOHEXANE AND ITS APPLICATION TO THE SYNTHESIS OF CHIRAL LACTONE MOIETY IN COMPACTIN

被引：25
作者：
SUEMUNE, H
TAKAHASHI, M
MAEDA, S
XIE, ZF
SAKAI, K
机构：
[1] Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka
来源：
TETRAHEDRON-ASYMMETRY | 1990年 / 1卷 / 07期
关键词：
D O I：
10.1016/S0957-4166(00)86344-2
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Asymmetric hydrolysis of meso diacetate 3 using pig liver esterase afforded (1S,3R,5S)-(-)-4, which was converted into chiral lactone moiety in compactin. © 1990.
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页码：425 / 428
页数：4
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