SYNTHESIS OF SOME 2-HYDROXY-3,5-DITERTBUTYLBENZAMIDES

A number of amides were synthesized from 2-hydroxy-3,5-ditertbutylbenzoyl chloride and the following secondary amines in excess: diethylamine, di-n-propylamine, di-isobutylamine, pyrrolidine and morfoline; the yields varied from 80 to 90%. The acyl halide was prepared from the acid using thionyl chloride and dimethylformamide as catalyst. Also the hidrazide was obtained in 70% yield by reaction of methyl 2-hydroxy-3,5-ditertbutylbenzoate and hidrazine. The compounds were characterized mainly by their IR, H-1-NMR and C-13-NMR spectra.