HEPATIC BLOOD-FLOW AND DRUG-METABOLISM IN PATIENTS ON ENZYME-INDUCING ANTICONVULSANTS

被引：72
作者：
PIRTTIAHO, HI
SOTANIEMI, EA
PELKONEN, RO
PITKANEN, U
机构：
[1] UNIV OULU,DEPT PHARMACOL,SF-90220 OULU 22,FINLAND
[2] UNIV OULU,DEPT RADIAT THERAPY,SF-90220 OULU 22,FINLAND
来源：
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY | 1982年 / 22卷 / 05期
关键词：
D O I：
10.1007/BF00542550
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：441 / 445
页数：5
相关论文
共 24 条
[1]   LIVER ENLARGEMENT AND DRUG TOXICITY [J].
BARKA, T ;
POPPER, H .
MEDICINE, 1967, 46 (02) :103-&
[2]   INCREASED CLEARANCE OF ANTIPYRINE AND D-PROPRANOLOL AFTER PHENOBARBITAL TREATMENT IN MONKEY - RELATIVE CONTRIBUTIONS OF ENZYME-INDUCTION AND INCREASED HEPATIC BLOOD-FLOW [J].
BRANCH, RA ;
SHAND, DG ;
WILKINSON, GR ;
NIES, AS .
JOURNAL OF CLINICAL INVESTIGATION, 1974, 53 (04) :1101-1107
[3]  
CAESAR J, 1961, CLIN SCI, V21, P43
[4]  
CONNEY AH, 1967, PHARMACOL REV, V19, P317
[5]  
Dobson E. L., 1952, ACTA MED SCAND S, V144
[6]   INFLUENCE OF PHENOBARBITAL ON TURNOVER OF HEPATIC MICROSOMAL CYTOCHROME B5 AND CYTOCHROME P-450 HEMES IN RAT [J].
GREIM, H ;
SCHENKMAN, JB ;
KLOTZBUCHER, M ;
REMMER, H .
BIOCHIMICA ET BIOPHYSICA ACTA, 1970, 201 (01) :20-+
[7]   CONTROLLED TRIAL OF PHETHARBITAL, A NON-HYPNOTIC BARBITURATE, IN UNCONJUGATED HYPERBILIRUBINAEMIA [J].
HUNTER, J ;
THOMPSON, RP ;
RAKE, MO ;
WILLIAMS, R .
BRITISH MEDICAL JOURNAL, 1971, 2 (5760) :497-&
[8]   INFLUENCE OF PHENOBARBITAL ON FACTORS RESPONSIBLE FOR HEPATIC CLEARANCE OF INDOCYANINE GREEN IN RAT - RELATIVE CONTRIBUTIONS OF INDUCTION AND ALTERED LIVER BLOOD-FLOW [J].
MCDEVITT, DG ;
NIES, AS ;
WILKINSON, GR .
BIOCHEMICAL PHARMACOLOGY, 1977, 26 (13) :1247-1250
[9]   STIMULANT EFFECT OF DRUGS ON INDOCYANINE GREEN CLEARANCE BY LIVER [J].
MELIKIAN, V ;
EDDY, JD ;
PATON, A .
GUT, 1972, 13 (10) :755-&
[10]  
OHNHAUS EE, 1976, ACTA HEPATO-GASTRO, V23, P404
123