12-MONTH FOLLOW-UP-STUDY OF REGIONAL CEREBRAL BLOOD-FLOW IN PARKINSONS-DISEASE

被引：21

作者：

TACHIBANA, H ^{[1
]}

TOMINO, Y ^{[1
]}

KAWABATA, K ^{[1
]}

SUGITA, M ^{[1
]}

FUKUCHI, M ^{[1
]}

机构：

[1] HYOGO MED UNIV,DEPT NUCL MED,NISHINOMIYA,HYOGO 663,JAPAN

来源：

DEMENTIA | 1995年 / 6卷 / 02期

关键词：

PARKINSONS DISEASE; CEREBRAL BLOOD FLOW; SINGLE-PHOTON EMISSION COMPUTED TOMOGRAPHY; LONGITUDINAL STUDY;

D O I：

10.1159/000106927

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Measurement of regional cerebral blood flow (rCBF) in 30 patients with Parkinson's disease using single-photon emission computed tomography and 123I-IMP demonstrated that hypoperfusion was relatively severer in the parietal cortex than other cortices before and after a 1-year follow-up period, The decline in the scores of the Mini-Mental State Examination was significantly correlated with the decrease in rCBF in the parietal cortex during the follow-up period. Our findings suggest that the parietal cortex is involved in the cognitive impairment in patients with Parkinson's disease.

引用

页码：89 / 93

页数：5

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