Hyperfractionated high-dose rate brachytherapy in the treatment of oral tongue cancer

被引：9

作者：

Tucek, Lubos ^{[1
]}

Petera, Jiri ^{[2
]}

Sirak, Igor ^{[2
]}

Vosmik, Milan ^{[2
]}

Dolezalova, Helena ^{[1
]}

Brokesova, Simona ^{[2
]}

Hodek, Miroslav ^{[2
]}

Kasaova, Linda ^{[2
]}

Paluska, Petr ^{[2
]}

机构：

[1] Univ Hosp, Dept Stomatol, Hradec Kralove, Czech Republic

[2] Univ Hosp, Dept Oncol & Radiotherapy, Sokolska 581, Hradec Kralove 50005, Czech Republic

来源：

REPORTS OF PRACTICAL ONCOLOGY AND RADIOTHERAPY | 2011年 / 16卷 / 06期

关键词：

Oral cancer; High-dose rate brachytherapy;

D O I：

10.1016/j.rpor.2011.07.001

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background: Low-dose rate brachytherapy is a well established treatment modality of oral cancer. Data about high-dose rate (HDR) brachytherapy are still sparse with various fractionation schedules and heterogeneous results. Aim: The aim of our retrospective study was to evaluate the results of HDR brachytherapy with doses of 3Gy twice daily. Patients and methods: Twenty patients with squamous cell tongue cancer were treated in the years 2001-2009 by exclusive HDR BT 18x3Gy twice daily. The plastic tube technique was used. Median follow up was 47 months (7.8-118) since brachytherapy. Results: The local and locoregional control was 85% and 68%, respectively. Bone necrosis developed in one case treated without mandibular shielding and soft tissue necrosis in 2 cases. Conclusion: It can be concluded that HDR brachytherapy with 18x3Gy twice daily is safe with promising local control. The risk of nodal recurrences is substantial. (C) 2011 Greater Poland Cancer Centre, Poland. Published by Elsevier Urban & Partner Sp. z.o.o. All rights reserved.

引用

页码：243 / 247

页数：5

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