INFLUENCE OF DIETETIC AND MEDICINAL THERAPY ON THE LEVEL OF CHOLESTEROL HIGH-DENSITY LIPOPROTEINS IN PRIMARY HYPERLIPOPROTEINEMIA

A 3-mo. fat-limiting diet did not alter the level of cholesterol high-density lipoproteins [CHDLP] in 25 patients with hyperlipoproteinemia. A fat- and carbohydrate-limiting diet decreased the weight, total cholesterol and triglyceride levels in 40 patients with primary triglyceridemia. Combined clofibrate and xanthinol nicotinate therapy decreased the triglyceride level, increased the CHDLP and left the cholesterol level unchanged. A combined diet and clofibrate and xanthinol therapy decreased the cholesterol and triglyceride content and cholesterol low-density lipoproteins and increased CHDLP and the CHDLP/cholesterol ratio. Adebit (butyl-biguanide) decreased CHDLP in blood. Biguanides were not recommended for treatment of primary hyperlipoproteinemia.