THE EFFECT OF TABLET SIZE ON THE GASTRIC-EMPTYING OF NONDISINTEGRATING TABLETS

被引：67

作者：

KHOSLA, R ^{[1
]}

DAVIS, SS ^{[1
]}

机构：

[1] UNIV NOTTINGHAM,DEPT PHARMACEUT SCI,NOTTINGHAM NG7 2RD,ENGLAND

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1990年 / 62卷 / 2-3期

关键词：

Gamma scintigraphy; Gastric emptying; Tablet size;

D O I：

10.1016/0378-5173(90)90243-W

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The gastrointestinal transit of non-disintegrating tablets of different sizes (7-13 mm diameter) was investigated in fed subjects using the technique of gamma scintigraphy. The 13 mm tablets took longer to empty from the stomach, with less variation between the individual data, than the smaller tablets. © 1990.

引用

页码：R9 / R11

页数：3

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