CEFTAZIDIME VS TOBRAMYCIN FOR SERIOUS INFECTIONS IN UROLOGICAL PATIENTS

被引：3
作者：
TAMMELA, T
KONTTURI, M
USENIUS, R
UUSIPENTTILA, S
VIITANEN, J
JAUHIAINEN, K
机构：
[1] JYVASKYLA CENT HOSP,UROL UNIT,OULU,FINLAND
[2] JOENSUU CENT HOSP,UROL UNIT,OULU,FINLAND
来源：
JOURNAL OF HOSPITAL INFECTION | 1990年 / 15卷
关键词：
D O I：
10.1016/0195-6701(90)90083-Z
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
A prospective, randomized study was undertaken to compare the efficacy and safety of tobramycin and ceftazidime in the treatment of serious infections in 77 urological patients. Of the 39 tobramycin-treated and 38 ceftazidime-treated patients, 74% and 82%, respectively, were cured clinically. Microbiological cure rates were 72% and 79%, respectively. Three patients treated with tobramycin and two treated with ceftazidime developed a significant superinfection. Both drugs were tolerated well. Because of potential ototoxicity and nephrotoxicity the use of aminoglycosides is less advantageous than ceftazidime for seriously infected urological patients. © 1990.
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页码：69 / 76
页数：8
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