INTRACYTOPLASMIC SPERM INJECTION, FERTILIZATION, AND EMBRYO-TRANSFER AFTER RETRIEVAL OF SPERMATOZOA BY TESTICULAR BIOPSY FROM AN AZOOSPERMIC MALE WITH TESTICULAR TUBULAR ATROPHY

被引：24
|
作者：
YEMINI, M
VANDERZWALMEN, P
MUKAIDA, T
SCHOENGOLD, S
BIRKENFELD, A
机构：
[1] DIAMOND INST INFERT & MENOPAUSE,IRVINGTON,NJ
[2] VAN HELMONT HOSP,SCHOYSMAN INFERTIL MANAGEMENT FDN,VILVOORDE,BELGIUM
来源：
FERTILITY AND STERILITY | 1995年 / 63卷 / 05期
关键词：
INTRACYTOPLASMIC SPERM INJECTION; TESTICULAR ATROPHY;
D O I：
10.1016/S0015-0282(16)57559-1
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Objective: To achieve fertilization and cleavage by spermatozoa retrieved by testicular biopsy from a male with testicular tubular atrophy. Design: Clinical trial. Setting: Private reproductive institute. Patient: Azoospermic male with demonstrated testicular tubular atrophy and almost complete spermatogenic arrest. Intervention: Open biopsy retrieval of testicular tissue and sperm followed by intracytoplasmic sperm injection. Main Outcome Measures: Fertilization and cleavage. Results: One four- to six-cell embryo was formed after intracytoplasmic sperm injection of five eggs with extruded polar bodies by retrieved sperm. Conclusion: Intracytoplasmic sperm injection after testicular sperm aspiration may be attempted in cases with severely decreased spermatogenesis and result in fertilization, cleavage, and embryo transfer.
引用
收藏
页码：1118 / 1120
页数：3
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