LICHEN-SCLEROSUS-ET-ATROPHICUS IN CHILDREN AND YOUNG-ADULTS

被引：36

作者：

HELM, KF ^{[1
]}

GIBSON, LE ^{[1
]}

MULLER, SA ^{[1
]}

机构：

[1] MAYO CLIN & MAYO FDN,DEPT DERMATOL,200 1ST ST SW,ROCHESTER,MN 55905

来源：

PEDIATRIC DERMATOLOGY | 1991年 / 8卷 / 02期

关键词：

D O I：

10.1111/j.1525-1470.1991.tb00294.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We performed a retrospective study of 52 children and young adults (average age 18 yrs) with lichen sclerosus et atrophicus. In 56% of patients the eruption was still present after a follow-up of 7.5 years. Younger patients were most likely to show improvement. The histologic appearance of both groups (patients with persistent lesions and those with resolution of lesions) showed classic features of lichen sclerosus et atrophicus: homogenized collagen with an underlying bandlike lymphocytic infiltrate. Epidermal changes such as atrophy, hyperplasia, and follicular plugging were slightly more prominent in patients with persistent lesions. Menarche, pregnancy, and the presence of extragenital lesions had no effect on the prognosis, but since the condition resolved, on average, during adolescence, unknown developmental factors may be implicated.

引用

页码：97 / 101

页数：5

共 27 条

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