AN EFFICIENT NEW CANNABINOID ANTIEMETIC IN PEDIATRIC ONCOLOGY

被引：122

作者：

ABRAHAMOV, A

MECHOULAM, R

机构：

[1] BIKUR CHOLIM HOSP, DEPT PEDIAT, JERUSALEM, ISRAEL

[2] HEBREW UNIV JERUSALEM, FAC MED, BRETTLER CTR MED RES, IL-91120 JERUSALEM, ISRAEL

来源：

LIFE SCIENCES | 1995年 / 56卷 / 23-24期

关键词：

TETRAHYDROCANNABINOL; VOMITING; DRONABINOL;

D O I：

10.1016/0024-3205(95)00194-B

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Delta-8-tetrahydrocannabinol (delta-8-THC), a cannabinoid with lower psychotropic potency than the main Cannabis constituent, delta-9-tetrahydrocannabinol (delta-9-THC), was administerd (18 mg/m2 in edible oil, p.o.) to eight children, aged 3-13 years with various hematologic cancers, treated with different antineoplastic drugs for up to 8 months. The total number of treatments with delta-8-THC so far is 480. The THC treatment started two hours before each antineoplastic treatment and was continued every 6 hrs for 24 hours. Vomiting was completely prevented. The side effects observed were negligible.

引用

页码：2097 / 2102

页数：6

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