ANTIOXIDATIVE AND ANTIINFLAMMATORY COMPOUNDS FROM TROPICAL GINGERS - ISOLATION, STRUCTURE DETERMINATION, AND ACTIVITIES OF CASSUMUNIN-A, CASSUMUNIN-B, AND CASSUMUNIN-C, NEW COMPLEX CURCUMINOIDS FROM ZINGIBER-CASSUMUNAR

被引：62

作者：

MASUDA, T

JITOE, A

机构：

[1] Faculty of Human Life Science, Osaka City University, Osaka 558, Sumiyoshi

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 1994年 / 42卷 / 09期

关键词：

ANTIINFLAMMATORY ANTIOXIDANTS; Z-CASSUMUNAR; CURCUMINOID;

D O I：

10.1021/jf00045a004

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

Assay-guided isolation gave three new compounds, cassumunins A, B, and C, having both antioxidant and antiinflammatory activities, from the rhizomes of a tropical ginger, Zingiber cassumunar. Antioxidant activity and antiinflammatory activity were measured using a thiocyanate method and a 12-O-tetradecanoylphorbol 13-acetate-induced method on mouse ear, respectively. The antioxidant activity of cassumunins A-C is stronger than that of curcumin, and their antiinflammatory activity is also stronger than that of curcumin. Spectroscopic analysis of cassumunins A-C revealed them to be a new type of complex curcumin. Antioxidant and antiinflammatory activities of cassumunins suggested that the substituted group at the 5'-position of curcumin increased both activities.

引用

页码：1850 / 1856

页数：7

共 20 条

[1] CHAIN-BREAKING PHENOLIC ANTIOXIDANTS - STERIC AND ELECTRONIC EFFECTS IN POLYALKYLCHROMANOLS, TOCOPHEROL ANALOGS, HYDROQUINONES, AND SUPERIOR ANTIOXIDANTS OF THE POLYALKYLBENZOCHROMANOL AND NAPHTHOFURAN CLASS [J].