THE DROSOPHILA-MELANOGASTER HOMOLOG OF RIBOSOMAL-PROTEIN L27A

The amino acid sequence of the Drosophila melanogaster 60S ribosomal sub-unit protein, L27a, was deduced from the sequence of nucleotides in a recombinant cDNA. Ribosomal protein L27a has 149 amino acids with a molecular weight of 17,123 Daltons. Hybridisation of the cDNA to polytene chromosomes indicates the presence of a single gene on chromosome 3R at 87F/88A. There is a single mRNA for the protein of around 650 nucleotides in length. Drosophila ribosomal protein L27a is homologous to the rat and yeast L27a and to the other members of the L15 ribosomal protein family. There is also significant homology with an invertebrate motor protein and a Drosophila photoreceptor morphogenesis protein. © 1994 Academic Press, Inc.