A NEW BIOACTIVE BONE-CEMENT CONSISTING OF BIS-GMA RESIN AND BIOACTIVE GLASS POWDER

被引：99
作者：
KAWANABE, K
TAMURA, J
YAMAMURO, T
NAKAMURA, T
KOKUBO, T
YOSHIHARA, S
机构：
[1] KYOTO UNIV,BIOMED ENGN RES CTR,53 KAWAHARA CHO,SAKYO KU,KYOTO 606,JAPAN
[2] KYOTO UNIV,FAC MED,DEPT ORTHOPED SURG,KYOTO 606,JAPAN
[3] KYOTO UNIV,FAC ENGN,DEPT IND CHEM,KYOTO 606,JAPAN
[4] NIPPON ELECT GLASS CO LTD,OTSU,JAPAN
来源：
JOURNAL OF APPLIED BIOMATERIALS | 1993年 / 4卷 / 02期
关键词：
D O I：
10.1002/jab.770040204
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
We have developed a bioactive bone cement consisting of silane-treated CaO-SiO2-P2O5-CaF2 glass powder as the filling particles and bisphenol-a-glycidyl methacrylate (BIS-GMA) diluted with triethylene-glycol dimethacrylate (TEGDMA) as the organic matrix. Histological examination demonstrated direct bonding between the cement and bone along the circumference of the cement at 4 weeks after implantation in rat tibia. The compressive strength and toughness of the cement were two and four times greater than those of polymethylmethacrylate (PMMA) cement, respectively. The inflammatory reaction of the skin caused by the new cement was not as intense as that for PMMA 3 days after subcutaneous implantation. This new cement may be applicable as a bioactive bone cement with high mechanical strength.
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页码：135 / 141
页数：7
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