EFFECTS OF ALPHA-ADRENERGIC AND BETA-ADRENERGIC ANTAGONISTS ON AGGRESSIVE-BEHAVIOR IN MALE-MICE

被引：0
作者：
ALMALIKI, SJ [1 ]
ALHAMOOD, MH [1 ]
机构：
[1] CTR REVIVAL SCI ARAB HERITAGE,BAGHDAD,IRAQ
来源：
AGGRESSIVE BEHAVIOR | 1993年 / 19卷 / 05期
关键词：
AGGRESSION; DEFENSE; ADRENERGIC RECEPTORS; MALE MICE;
D O I：
10.1002/1098-2337(1993)19:5<361::AID-AB2480190505>3.0.CO;2-M
中图分类号：
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号：
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要：
The effects of a variety of alpha and beta adrenergic antagonists were examined on the social encounters of isolated male mice with anosmic male partners. A range of alpha antagonists, including phentolamine, prazosin, and yohimbine, all suppressed social aggression. A range of beta antagonists, including propranolol, atenolol, metaprolol, and ICI 118,551, also reduced this type of attack. Ethological assessment of the lowest effective dose of these adrenergic antagonists revealed a marked inhibitor action on offensive, social, and nonsocial behavior, while defensive responses and immobility were enhanced. It is concluded that the noradrenergic system has a significant non-specific role in mediating intermale aggression via both alpha and beta adrenergic receptor subtypes. (C) 1993 Wiley-Liss, Inc.
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页码：361 / 367
页数：7
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