Two patients with a slowly progressive and severe motor apraxia are presented. In one case, there was only apraxia; in the other there was moderate memory disturbance and a mild decline of global intellectual ability, suggesting a more widespread cognitive dysfunction. In this second case, recognition of the correct use of objects was also severely impaired, suggesting a disturbance of motor knowledge. In both cases, apraxia was asymmetrical, and associated with a contralateral atrophy of the upper parietal cortex, suggesting a differential involvement of separate action systems for each hand.
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Mayo Clin, Dept Neurol, Div Behav Neurol, Rochester, MN 55905 USA
Mayo Clin, Dept Neurol, Div Movement Disorders, Rochester, MN USAMayo Clin, Dept Neurol, Div Behav Neurol, Rochester, MN 55905 USA
Josephs, Keith A.
Duffy, Joseph R.
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Mayo Clin, Dept Neurol, Div Speech Pathol, Rochester, MN USAMayo Clin, Dept Neurol, Div Behav Neurol, Rochester, MN 55905 USA
Duffy, Joseph R.
Strand, Edythe A.
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Mayo Clin, Dept Neurol, Div Speech Pathol, Rochester, MN USAMayo Clin, Dept Neurol, Div Behav Neurol, Rochester, MN 55905 USA
Strand, Edythe A.
Machulda, Mary M.
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Mayo Clin, Dept Psychiat & Psychol, Div Neuropsychol, Rochester, MN USAMayo Clin, Dept Neurol, Div Behav Neurol, Rochester, MN 55905 USA
Machulda, Mary M.
Senjem, Matthew L.
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Mayo Clin, Dept Informat Technol, Rochester, MN USAMayo Clin, Dept Neurol, Div Behav Neurol, Rochester, MN 55905 USA
Senjem, Matthew L.
Lowe, Val J.
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Mayo Clin, Dept Radiol, Div Nucl Med, Rochester, MN USAMayo Clin, Dept Neurol, Div Behav Neurol, Rochester, MN 55905 USA
Lowe, Val J.
Jack, Clifford R., Jr.
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Mayo Clin, Dept Radiol, Div Neuroradiol, Rochester, MN USAMayo Clin, Dept Neurol, Div Behav Neurol, Rochester, MN 55905 USA
Jack, Clifford R., Jr.
Whitwell, Jennifer L.
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Mayo Clin, Dept Radiol, Div Neuroradiol, Rochester, MN USAMayo Clin, Dept Neurol, Div Behav Neurol, Rochester, MN 55905 USA
机构:
Greater Manchester Neurosci Ctr, Cerebral Funct Unit, Salford, Lancs, England
Univ Manchester, Sch Community Based Med, Mental Hlth & Neurodegenerat Res Grp, Manchester, Lancs, EnglandGreater Manchester Neurosci Ctr, Cerebral Funct Unit, Salford, Lancs, England