Management of Persistent Hyponatremia Induced by Long-acting Injectable Risperidone Therapy

被引：1

作者：

Chowdhury, Waliul ^{[1
]}

Lodhi, Muhammad Uzair ^{[1
]}

Kuzel, Aaron R. ^{[2
]}

Johnson, Peter ^{[3
]}

Rahim, Umar ^{[4
]}

Rahim, Mustafa ^{[5
]}

机构：

[1] Raleigh Gen Hosp, Dept Med, Beckley, WV 25801 USA

[2] Lincoln Mem Univ, Debusk Coll Osteopath Med, Dept Emergency Med, Harrogate, TN USA

[3] Lincoln Mem Univ, Raleigh Gen Hosp, Beckley, WV USA

[4] Queens Univ Charlotte, Dept Sci, Charlotte, NC USA

[5] West Virginia Univ, Sch Med, Internal Med, Morgantown, WV USA

来源：

CUREUS | 2018年 / 10卷 / 05期

关键词：

family medicine; psychiatry; siadh; hyponatremia; tolvaptan; demeclocycline; management of persistent hyponatremia; preventive medicine;

D O I：

10.7759/cureus.2657

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We present the case of a 55-year-old Caucasian male with a history of schizophrenia presenting with severe hyponatremia attributed to long-acting injectable risperidone treatment. Antipsychotic-induced hyponatremia is an uncommon but serious side effect that should be considered when assessing individuals on chronic psychiatric regimens. In this report, we will discuss our treatment plan for the patient when water deprivation and hypertonic saline failed to correct his scrum sodium levels. The goal of this case report is to raise awareness of severe hyponatremia as a side effect of long-acting risperidone, and to encourage further studies to create guidelines for its management when current protocols fail to correct sodium levels.

引用

页数：6

共 8 条

[1] Amphetamine reinstates polydipsia induced by chronic exposure to quinpirole, a dopaminergic D2 agonist, in rats [J].