SYNTHESIS OF STEROIDAL NITROSOUREAS WITH ANTI-TUMOR ACTIVITY

被引：50

作者：

LAM, HYP

BEGLEITER, A

GOLDENBERG, GJ

WONG, CM

机构：

[1] UNIV MANITOBA,DEPT CHEM,WINNIPEG R3T 2N2,MANITOBA,CANADA

[2] MANITOBA INST CELL BIOL,WINNIPEG R3E OV9,MANITOBA,CANADA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1979年 / 22卷 / 02期

关键词：

D O I：

10.1021/jm00188a015

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Four steroidal nitrosoureas with structures which may permit specific binding to estrogen receptor were synthesized. Inhibitory activity was observed against the growth of the DMBA-induced transplantable rat mammary tumor 13762. © 1979, American Chemical Society. All rights reserved.

引用

页码：200 / 202

页数：3

共 20 条

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