EXPRESSION OF PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) AND NUCLEOLAR ORGANIZER REGIONS (NORS) IN MULTIPLE-MYELOMA

被引：0

作者：

SKOPELITOU, A

TSELENIS, S

THEOCHARIS, S

AGNANTIS, N

TSENGA, A

ELEMENOGLOU, J

HADJIYANNAKIS, M

KITTAS, C

机构：

[1] UNIV ATHENS,SCH MED,DEPT PATHOL,HAEMATOPATHOL SECT,GR-11527 GOUDI,GREECE

[2] UNIV IOANNINA,SCH MED,DEPT PATHOL,GR-45110 IOANNINA,GREECE

[3] TZANEION GEN HOSP,DEPT PATHOL,PIRAEUS,GREECE

[4] UNIV ATHENS,SCH MED,DEPT PATHOL PHYSIOL,GR-11527 GOUDI,GREECE

来源：

ANTICANCER RESEARCH | 1994年 / 14卷 / 3A期

关键词：

MULTIPLE MYELOMA; PCNA; AGNORS;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We have studied 72 cases of multiple myeloma (MM) bone marrow trephine biopsies using the monoclonal antibody PC-10 and the colloid silver nitrate method for identification of proliferating cell nuclear antigen (PCNA) and nucleolar organizer regions (NORs), respectively. PC-10 and AgNOR scores were statistically significantly different between low versus intermediate and low versus high grade of malignancy (P<0.001), whereas their difference was not significant between intermediate and high grade. A strong correlation was identified between these two proliferation-associated indices in each histological grade. There is evidence that the proliferative state of myelomas belonging to the intermediate grade is approximately the same as that observed in high grade (blastic) ones.

引用

页码：787 / 792

页数：6

共 50 条

[21] PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) EXPRESSION IN CHRONIC LYMPHOCYTIC-LEUKEMIA (CLL)
DELGIGLIO, A
OBRIEN, S
FORD, RJ
MANNING, J
SAYA, H
KEATING, M
JOHNSTON, D
CHAMONE, DF
DEISSEROTH, AB
LEUKEMIA & LYMPHOMA, 1993, 10 (4-5) : 265 - 271
[22] The clinical significance of autoantibodies to the proliferating cell nuclear antigen (PCNA)
Mahler, Michael
Miyachi, Kiyomitsu
Peebles, Carol
Fritzler, Marvin J.
AUTOIMMUNITY REVIEWS, 2012, 11 (10) : 771 - 775
[23] Expression of proliferating cell nuclear antigen (PCNA) and apoptosis related antigen (LeY) in epithelial skin tumors
Tsuji, T
Kitajima, S
Koashi, Y
AMERICAN JOURNAL OF DERMATOPATHOLOGY, 1998, 20 (02) : 164 - 169
[24] Proliferating cell nuclear antigen (PCNA):: a dancer with many partners
Maga, G
Hübscher, U
JOURNAL OF CELL SCIENCE, 2003, 116 (15) : 3051 - 3060
[25] Assessment of potential doubling time (T-pot), argyrophilic nucleolar organizer regions (AgNOR), and proliferating cell nuclear antigen (PCNA) as predictors of therapy response in canine non-Hodgkin's lymphoma
Vail, DM
Kisseberth, WC
Obradovich, JE
Moore, FM
London, CA
MacEwen, EG
Ritter, MA
EXPERIMENTAL HEMATOLOGY, 1996, 24 (07) : 807 - 815
[26] Comparison of Proliferating Cell Nuclear Antigen (PCNA) Expression among Nasal Polyp and Chronic Rhinosinusitis
Barouh, Alireza
Nadoushan, Mohammadreza Jalali
Soltanipur, Masood
ACTA OTORRINOLARINGOLOGICA ESPANOLA, 2024, 75 (05): : 310 - 315
[27] Proliferating cell nuclear antigen (PCNA) expression and serum IL-8 product in leiomyomas
Albiaty, Huda Sadoon Jassim
Al-Ammiri, Hind H.
Salman, Ali yhea
TRANSPLANT IMMUNOLOGY, 2025, 88
[28] Proliferating cell nuclear antigen (PCNA) expression in pituitary adenomas: relationship to the endocrine phenotype of adenoma
Pawlikowski, M
Gruszka, A
Kurnatowska, I
Winczyk, K
Kunert-Radek, J
Radek, A
FOLIA HISTOCHEMICA ET CYTOBIOLOGICA, 2006, 44 (01) : 37 - 41
[29] ARGYROPHILIC NUCLEOLAR ORGANIZER REGION COUNTS AND PROLIFERATING CELL NUCLEAR ANTIGEN SCORES ARE 2 RELIABLE INDICATORS OF SURVIVAL IN PHARYNGEAL CARCINOMA
PICH, A
CHIUSA, L
PISANI, P
KRENGLI, M
PIA, F
NAVONE, R
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 1992, 119 (02) : 106 - 110
[30] PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) IN MEDULLARY-THYROID CARCINOMA
SKOPELITOU, A
KORKOLOPOULOU, P
PAPANIKOLAOU, A
HADJIYANNAKIS, M
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 1993, 119 (07) : 379 - 381

← 1 2 3 4 5 →