In the title compound, [Ni(C12H6O4)(C21H18N4)(H2O)](n), the Ni-II cation is coordinated by three carboxylate O atoms of two naphthalene-1,4-dicarboxylate anions, one water molecule and two N atoms of two 1,10-(9,9-dimethyl-9H-fluoren-2,7diyl) di-1H-imidazole (DFDI) ligands, giving rise to a slightly distorted octahedral geometry. The Ni-II ions are linked by the DFDI ligands into chains, which are further connected by the carboxylate anions into double chains that elongate in the the b-axis direction. These double chains are linked by centro-symmetric pairs of O-H center dot center dot center dot O hydrogen bonds into layers parallel to (10 (1) over bar). The asymmetric unit consists of one crystallographically independent Ni-II cation, one carboxylate and one DFDI ligand, as well as of one water molecule, all of them located in general positions.