SYNTHESIS OF HIGHLY FUNCTIONALIZED 3,4-DIHYDRO-2H-PYRANS BY HIGH-PRESSURE LEWIS-ACID CATALYZED CYCLOADDITION OF ENOL ETHERS AND ALPHA,BETA-UNSATURATED ALDEHYDES

被引：13
|
作者：
VANDENPUT, DAL [1 ]
SCHEEREN, HW [1 ]
机构：
[1] CATHOLIC UNIV NIJMEGEN,NSR,CTR MOLEC STRUCT DESIGN & SYNTH,DEPT ORGAN CHEM,6525 ED NIJMEGEN,NETHERLANDS
来源：
TETRAHEDRON | 1995年 / 51卷 / 30期
关键词：
D O I：
10.1016/0040-4020(95)00449-I
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
New highly substituted 3,4-dihydro-2H-pyrans were synthesized with high ENDO selectivity by high pressure hetero Diels Alder reactions of alpha,beta-unsaturated aldehydes and enol ethers in the presence of lanthanide-catalysts. Chiral induction was studied using chiral catalysts, a chiral enol ether and a combination of these chiralities.
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收藏
页码：8383 / 8388
页数：6
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