Objective: This review discusses aspects of the intention to become pregnant, pregnancy itself, delivery and the postpartum period in patients with multiple sclerosis. Methods: The search was done in the following databases: MEDLINE, THE COCHRANE LIBRARY, EMBASE, LILACS, SciSEARCH, and in references to the most relevant papers in the past ten years. The following terms were used for the research: multiple sclerosis, pregnancy, breastfeeding, beta interferon, glatiramer acetate. Results: Thirty three specific papers on this theme were found, including the international consensus on the treatment of multiple sclerosis. Themes like prenatal, delivery and postnatal management were analyzed. Conclusion: The articles highlight that treatment with immunomodulators is discouraged, and that corticosteroid pulsed therapy is recommended for eventual attacks. Breast feeding, though not encouraged is not formally contraindicated.