HISTAMINE - ITS METABOLISM AND LOCALIZATION IN MAMMARY-GLAND

被引：24

作者：

MASLINSKI, C ^{[1
]}

KIERSKA, D ^{[1
]}

FOGEL, WA ^{[1
]}

KINNUNEN, A ^{[1
]}

PANULA, P ^{[1
]}

机构：

[1] UNIV HELSINKI,DEPT ANAT,SF-00170 HELSINKI 17,FINLAND

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY | 1993年 / 105卷 / 02期

关键词：

D O I：

10.1016/0742-8413(93)90206-Z

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. Mammary gland of mouse (Mus musculus), rat (Rattus rattus), guinea pig (Cavia porcellus), cow (Bos taurus) and pig (Sus scrofa) contains different but always high concentrations of histamine. 2. Generally, the tissue histamine is localized in mast cells, although non-mast cell histamine immuno-reactivity is also present in mammary glands of the mouse, cow and pig. No histamine immunoreactive nerves could be detected. 3. Mammary glands are able to synthesize and inactivate histamine; the activity of specific histidine decarboxylase and at least one of the catabolizing enzyme-could be demonstrated. 4. Histamine fulfils basic criteria for being involved in physiological function of mammary glands.

引用

页码：269 / 273

页数：5

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