NEUTRALIZING MONOCLONAL-ANTIBODIES AGAINST ALPHA AND BETA SUBUNITS OF THE USTILAGO-MAYDIS VIRUS ENCODED TOXIN

被引：1
|
作者：
GINZBERG, I
ROSENBLUM, S
KOLTIN, Y
SMORODINSKY, NI
机构：
[1] TEL AVIV UNIV,GS WISE FAC LIFE SCI,DEPT MICROBIOL BIOTECHNOL,IL-69978 TEL AVIV,ISRAEL
[2] TEL AVIV UNIV,DR GEORGE S WISE CTR LIFE SCI,HYBRIDOMA UNIT,TEL AVIV,ISRAEL
来源：
VIRUS GENES | 1992年 / 6卷 / 03期
关键词：
MONOCLONAL ANTIBODIES; USTILAGO-MAYDIS; DSRNA VIRUS; FUNGAL TOXINS;
D O I：
10.1007/BF01702565
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The toxins secreted by Ustilago maydis are encoded by dsRNA viruses. The KP6 toxin encoded by subtype P6 consists of two polypeptides alpha and beta, which are not covalently bound. Neutralizing monoclonal antibodies (MoAbs) were raised against each subunit. Some of the anti-beta MoAbs identify different epitopes in the antigen. The MoAbs were used to affinity purify ot and beta-polypeptides from culture media and to detect the precursor of the mature toxin.
引用
收藏
页码：273 / 280
页数：8
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