Naphthalene Toxicity: Methemoglobinemia and Acute Intravascular Hemolysis

被引：25

作者：

Volney, Giselle ^{[1
]}

Tatusov, Michael ^{[2
]}

Yen, Andy C. ^{[3
]}

Karamyan, Nune ^{[4
]}

机构：

[1] Ross Univ, Sch Med, Internal Med, Roseau, Dominica

[2] Univ Maryland, Sch Med, Med Trauma & Crit Care, Baltimore, MD 21201 USA

[3] Ross Univ, Sch Med, Internal Med, Baltimore, MD USA

[4] Univ Maryland, Prince Georges Hosp Ctr, Internal Med, Cheverly, MD USA

来源：

CUREUS | 2018年 / 10卷 / 08期

关键词：

naphthalene; hemolysis; kidney injury; methemoglobinemia; ascorbic acid; toxicity; moth balls;

D O I：

10.7759/cureus.3147

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Naphthalene poisoning is a rare form of toxicity that may occur after ingestion, inhalation, or dermal exposure to naphthalene-containing compounds such as mothballs. Clinically, patients present with acute onset of dark brown urine, watery diarrhea, and non-bloody bilious vomiting 48-96 hours after exposure. Vital sign abnormalities include fever, tachycardia, hypotension, and persistent pulse oximetry readings of 84%-85% despite oxygen supplementation. Laboratory workup demonstrates hyperbilirubinemia with indirect predominance, hemolytic anemia, methemoglobinemia, and renal dysfunction. Treatment options include supportive care, red cell transfusion, ascorbic acid, methylene blue, and N-acetylcysteine. We present a case of naphthalene toxicity in a 20-year-old autistic male, who improved with supportive care, red blood cell transfusion, and ascorbic acid.

引用

页数：6

共 13 条

[1] Severe Methemoglobinemia Detected by Pulse Oximetry [J].