CRYSTALLIZATION OF THE FAB FRAGMENTS OF ANTIPEPTIDE MONOCLONAL-ANTIBODIES AND A COMPLEX WITH PEPTIDE

被引：3

作者：

GRIEST, RE ^{[1
]}

JEFFREY, PD ^{[1
]}

TAYLOR, GL ^{[1
]}

REES, AR ^{[1
]}

机构：

[1] LAB MOLEC BIOPHYS,OXFORD OX1 3QU,ENGLAND

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1992年 / 223卷 / 01期

关键词：

CRYSTALLIZATION; LYSOZYME; ANTIBODIES; PEPTIDE ANTIGEN; FAB FRAGMENTS;

D O I：

10.1016/0022-2836(92)90740-B

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The antigen-binding fragments of four monoclonal antibodies that cross-react with both the "loop" peptide of hen egg-white lysozyme (residues 57 to 84) against which they were raised, and with the native protein (HEL) have been crystallized. One of these fragments also crystallizes as a complex with the peptide antigen. © 1992.

引用

页码：381 / 382

页数：2

共 7 条

[1] NUCLEOTIDE-SEQUENCES OF 5 ANTI-LYSOZYME MONOCLONAL-ANTIBODIES [J].