SALT-INDUCED FORMATION OF MIXED PEPTIDES UNDER POSSIBLE PREBIOTIC CONDITIONS

被引：40

作者：

SCHWENDINGER, MG ^{[1
]}

RODE, BM ^{[1
]}

机构：

[1] UNIV INNSBRUCK,INST INORGAN & ANALYT CHEM,INNRAIN 52A,A-6020 INNSBRUCK,AUSTRIA

来源：

INORGANICA CHIMICA ACTA | 1991年 / 186卷 / 02期

关键词：

D O I：

10.1016/S0020-1693(00)85429-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Investigations on the copper mediated peptide formation in aqueous solution in the presence of high amounts of NaCl have been extended to systems simultaneously containing glycine and alanine. Preferential formation of ala-gly compared to gly-ala is observed, total yields as high as 10.5% and 5.8% of initial glycine and alanine are found, and various tripeptides also form. Racemization occurs only to a limited extent.

引用

页码：247 / 251

页数：5

共 21 条

[1] SUBMARINE HYDROTHERMAL VENTS AND ASSOCIATED GRADIENT ENVIRONMENTS AS SITES FOR THE ORIGIN AND EVOLUTION OF LIFE [J].

BAROSS, JA ;

HOFFMAN, SE .

ORIGINS OF LIFE AND EVOLUTION OF THE BIOSPHERE, 1985, 15 (04) :327-345

[2] PEPTIDE KINETICS .10. KINETICS OF SIMULTANEOUS HYDROLYSIS AND REVERSIBLE SEQUENCE-INVERSION OF SOME DIPEPTIDES IN STRONG ACID [J].

BREWERTON, AA ;

LONG, DA ;

TRUSCOTT, TG .

TRANSACTIONS OF THE FARADAY SOCIETY, 1970, 66 (573) :2297-+

[3] ROLE OF OXYGEN AND NITROGEN BASES IN LYSIS OF ACYL-ACTIVATED ESTERS - COBALT(III) CHELATED GLYCINE ISOPROPYL ESTER [J].

BUCKINGHAM, DA ;

FOSTER, DM ;

SARGESON, AM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1970, 92 (19) :5701-+

[4] PREBIOTIC ATMOSPHERIC OXYGEN LEVELS [J].

CARVER, JH .

NATURE, 1981, 292 (5819) :136-138

[5]

Fox S. W., 1977, MOL EVOLUTION ORIGIN

[6] PREBIOTIC CONDENSATION-REACTIONS IN AN AQUEOUS-MEDIUM - REVIEW OF CONDENSING AGENTS [J].

HULSHOF, J ;

PONNAMPERUMA, C .

ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES, 1976, 7 (03) :197-224

[7] PEPTIDE KINETICS .3. ACID CATALYSED HYDROLYSIS OF GLYCYL-GLYCYL-PHENYLALANINE [J].

LONG, DA ;

TRUSCOTT, TG .

TRANSACTIONS OF THE FARADAY SOCIETY, 1963, 59 (488) :1833-&

[8] EVOLUTION OF THE ENVIRONMENT AND ITS INFLUENCE ON THE EVOLUTION OF LIFE [J].

OCHIAI, EI .

ORIGINS OF LIFE AND EVOLUTION OF THE BIOSPHERE, 1978, 9 (02) :81-91

[9]

OIE T, 1982, Journal of the American Chemical Society, V104, P6169, DOI 10.1021/ja00387a001

[10] QUANTUM CHEMICAL STUDIES OF A MODEL FOR PEPTIDE-BOND FORMATION .2. ROLE OF AMINE CATALYST IN FORMATION OF FORMAMIDE AND WATER FROM AMMONIA AND FORMIC-ACID [J].

OIE, T ;

LOEW, GH ;

BURT, SK ;

MACELROY, RD .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (08) :2221-2227

← 1 2 3 →