High-salt intake during pregnancy may influence the outcome of renal ischemia/reperfusion in in adult offspring

被引:1
|
作者
Shahzamani, Felora [1 ,2 ]
Monajemi, Ramesh [2 ]
Nematbakhsh, Mehdi [1 ,3 ,4 ]
机构
[1] Isfahan Univ Med Sci, Water & Electrolytes Res Ctr, Esfahan, Iran
[2] Islamic Azad Univ, Dept Biol, Falavarjan Branch, Esfahan, Iran
[3] Isfahan Univ Med Sci, Dept Physiol, Esfahan, Iran
[4] Isfahan Inst Basic & Appl Sci Res, Esfahan, Iran
来源
JOURNAL OF RENAL INJURY PREVENTION | 2018年 / 7卷 / 02期
关键词
Salt diet; Pregnancy; Offspring; Ischemia/reperfusion;
D O I
10.15171/jrip.2018.17
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Introduction: The salt diet during the pregnancy may disturb the adult offspring's organs functions. Objectives: This study was designed to determine the role of high salt intake during pregnancy on the outcome of renal ischemia reperfusion (IR) in adult offspring. Materials and Methods: Renal IR was induced in 55 adult male and female offspring from mothers who intake high salt or normal drinking water during pregnancy, and the kidney function was evaluated. Results: Salt intake during pregnancy increased the serum levels of creatinine (Cr) and blood urea nitrogen (BUN) and decreased creatinine clearances (ClCr) level in offspring after renal IR gender dependently. Conclusion: The structural change in kidney of offspring from mothers who were subjected to salt intake during pregnancy may influence the outcomes of offspring's kidney functions after renal IR.
引用
收藏
页码:69 / 72
页数:4
相关论文
共 50 条
  • [21] High salt intake in pregnancy alters maturation of glomeruli in the rat offspring
    Koleganova, N.
    Piecha, G.
    Ritz, E.
    Schirmacher, P.
    Gross, M.
    VIRCHOWS ARCHIV, 2009, 455 : 77 - 78
  • [22] HIGH SALT INTAKE IN PREGNANCY ALTERS MATURATION OF GLOMERULI IN THE RAT OFFSPRING
    Koleganova, N.
    Piecha, G.
    Ritz, E.
    Mueller, A.
    Schirmacher, P.
    Gross, M. -L.
    JOURNAL OF HYPERTENSION, 2009, 27 : S176 - S176
  • [23] HIGH SALT INTAKE IN PREGNANCY ALTERS MATURATION OF GLOMERULI IN THE RAT OFFSPRING
    Koleganova, N.
    Piecha, G.
    Ritz, E.
    Mueller, A.
    Schirmacher, P.
    Gross, M.
    PEDIATRIC NEPHROLOGY, 2009, 24 (09) : 1883 - 1884
  • [24] Is High Salt Intake in Pregnancy Responsible for Altered Kidney Morphology in the Offspring?
    Koleganova, N.
    Piecha, G.
    Ritz, E.
    Gross, M. L.
    JOURNAL FUR HYPERTONIE, 2009, 13 (03): : 12 - 16
  • [25] Low salt intake during pregnancy and lactation causes changes in energy metabolism in adult female Wistar offspring
    Lopes Jang, Karen Lucasechi
    Shinohara Furukawa, Luzia Naoko
    Dolnikoff, Miriam Stermann
    Heimann, Joel Claudio
    FASEB JOURNAL, 2010, 24
  • [26] Blood pressure (BP) and insulin sensitivity (IS) in adult offspring are influenced by maternal salt intake during pregnancy and lactation
    Vidonho, AF
    Carrilho, BD
    Furukawa, LNS
    da Silva, AA
    Bergamaschi, CDT
    de Campos, RR
    Heimann, JC
    FASEB JOURNAL, 2003, 17 (04): : A450 - A450
  • [27] High Salt Diet During Pregnancy Alters Kidney Renin Granules In The Adult Rats Offspring
    Costa, Nauilo Lima
    Ramos, Debora Rothstein
    Lopes, Karen Lucasechi
    Naoko, Luzia
    Furukawa, Shinohara
    Heimann, Joel Claudio
    FASEB JOURNAL, 2008, 22
  • [28] High and Low Salt Intake during Pregnancy: Impact on Cardiac and Renal Structure in Newborns
    Seravalli, Priscila
    de Oliveira, Ivone Braga
    Zago, Breno Calazans
    de Castro, Isac
    Veras, Mariana Matera
    Alves-Rodrigues, Edson Nogueira
    Heimann, Joel C.
    PLOS ONE, 2016, 11 (08):
  • [29] High-salt intake and the renal expression of amino acid transporters in spontaneously hypertensive rats
    Pinho, Maria Joao
    Serrao, Maria Paula
    Soares-da-Silva, Patricio
    AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2007, 292 (05) : F1452 - F1463
  • [30] Maternal high-fructose intake during pregnancy and lactation induces metabolic syndrome in adult offspring
    Koo, Soohyeon
    Kim, Mina
    Cho, Hyun Min
    Kim, Inkyeom
    NUTRITION RESEARCH AND PRACTICE, 2021, 15 (02) : 160 - 172